New artificial connective matrix-like structure: thrombogenicity and use as endothelial cell culture support.

Bordenave, L; Lefebvre, F; Bareille, R; Rouais, F; Baquey, C; Rabaud, M · Biomaterials · 1992

basic_science · Level V

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Abstract

The recently described artificial connective matrix made of elastin solubilized peptides, type I+III collagens and connective proteins is shown to have structural and biological properties very close to the natural arterial subendothelium: the capacity to promote endothelial cell cultures maintaining their phenotype expression and its non-thrombogenicity. This new bioactive composite material could be used to replace arteries.

Medical subject headings