Tolerance of high-dose (3,000 mg/day) coenzyme Q10 in ALS.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 16344537.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
An open-label dose-escalation trial was performed to assess the safety and tolerability of high doses of coenzyme Q10 (CoQ10) in ALS. CoQ10, a cofactor in mitochondrial electron transfer, may improve the mitochondrial dysfunction in ALS. In this study, CoQ10 was safe and well tolerated in 31 subjects treated with doses as high as 3,000 mg/day for 8 months.
Medical subject headings
- Amyotrophic Lateral Sclerosis
- Central Nervous System
- Nerve Degeneration
- Neurons
- Neuroprotective Agents
- Ubiquinone