Male/female differences in indomethacin effects in preterm infants.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 16356449.
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Abstract
To test whether indomethacin prophylaxis has sex-mediated effects on severe intraventricular hemorrhage (grade III and IV) and on long-term outcomes in extremely-low-birth-weight infants. A secondary analysis was performed in the entire "Trial of Indomethacin Prophylaxis in Preterms study" cohort. The results suggest a weak differential treatment effect of indomethacin by sex.
Medical subject headings
- Anti-Inflammatory Agents, Non-Steroidal
- Cerebral Ventricles
- Developmental Disabilities
- Indomethacin
- Infant, Premature
- Infant, Very Low Birth Weight
- Intracranial Hemorrhages