SEAN: SNP prediction and display program utilizing EST sequence clusters.
basic_science · Level V
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- Record sourced from PubMed, PMID 16357032.
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Abstract
SEAN is an application that predicts single nucleotide polymorphisms (SNPs) using multiple sequence alignments produced from expressed sequence tag (EST) clusters. The algorithm uses rules of sequence identity and SNP abundance to determine the quality of the prediction. A Java viewer is provided to display the EST alignments and predicted SNPs.
Medical subject headings
- DNA Mutational Analysis
- Expressed Sequence Tags
- Polymorphism, Single Nucleotide
- Sequence Alignment
- Sequence Analysis, DNA
- Software
- User-Computer Interface