Role of the aldosterone-sensitive distal nephron in the sodium retention associated with liver cirrhosis.
editorial · Level V
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Abstract
The renal mechanisms underlying sodium retention during liver cirrhosis have been difficult to elucidate. Kim and associates describe a biphasic pattern of regulation of the renal epithelial sodium channel in the common bile duct ligation model, shedding some light on this issue.
Medical subject headings
- Aldosterone
- Kidney Tubules, Distal
- Liver Cirrhosis, Experimental
- Nephrons
- Sodium