Treatment of corticosteroid dependent optic neuropathy with intravenous immunoglobulin.

Kurz, Daryl; Egan, Robert A; Rosenbaum, James T · Am J Ophthalmol · 2005

case_report · Level V

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Abstract

To report a patient with corticosteroid dependent optic neuropathy treated with intravenous immunoglobulin (IVIg). Interventional case report. Records review. A 25-year-old woman developed bilateral vision loss with pain on eye movement in association with disk edema, dilated retinal veins, and hemorrhage. The vision improved markedly with prednisone, but she required a minimum of 20 mg/d despite concomitant therapy with methotrexate, cyclosporine, and/or mycophenolate mofetil. IVIg, 0.5 g/kg/d for 3 days each month with subsequent reduction in frequency, allowed discontinuation of all immunosuppression. Corticosteroid dependent optic neuropathy was successfully treated with IVIg.

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