Performing vitreous biopsy by perfluorocarbon-perfused vitrectomy.
cross_sectional · Level IV
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Abstract
To evaluate the safety and efficacy of perfluorocarbon-perfused vitrectomy (PCPV) as a novel technique in obtaining a large undiluted vitreous biopsy. Cross-sectional interventional study. Patients with undiagnosed posterior uveitis scheduled for vitreous biopsy underwent PCPV. A syringe containing 5 ml of perfluorocarbon liquid (PCL) was connected to the infusion line. Aspiration of the central and superior vitreous was initiated with simultaneous infusion of the PCL. Twenty eyes of 20 patients were included in this study. The mean +/- SD amount of PCL used in each eye was 4.50 +/- 0.69 ml. The volume of vitreous sample obtained in each eye was 2.25 +/- 0.413 ml. No complications occurred. PCPV is a safe and effective method for obtaining large undiluted vitreous biopsy.
Medical subject headings
- Biopsy, Needle
- Fluorocarbons
- Uveitis, Posterior
- Vitrectomy
- Vitreous Body