Sweet's syndrome responding to cyclosporin.

Bourke, J F; Berth-Jones, J; Graham-Brown, R A · Br J Dermatol · 1992

case_report · Level V

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Abstract

We report a case of Sweet's syndrome which responded to treatment with cyclosporin 4 mg/kg/day. Cyclosporin is effective in the treatment of many dermatoses, and although the immunosuppressive effects of cyclosporin are mainly attributed to inhibition of T-lymphocyte proliferation, it has also been shown to affect the functions of both neutrophils and monocytes. Possible mechanisms of action of cyclosporin in Sweet's syndrome are discussed.

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