Playing ping pong with pins: cortical and microtubule-induced polarity.
editorial · Level V
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Abstract
Cortical cell polarity controls mitotic spindle orientation in many cell types. In this issue of Cell, it is turned around and shown that the transfer of polarity information between the cortex and the spindle is not just one way. In Drosophila neuroblasts, the spindle also has polarizing activity on the cortex.
Medical subject headings
- Cell Polarity
- Drosophila Proteins
- Guanine Nucleotide Dissociation Inhibitors
- Microtubules
- Neurons
- Spindle Apparatus
- Stem Cells