Control of transcription through intragenic patterns of nucleosome composition.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 16377560.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Several recent papers show that differences in histone modification and the use of histone variants at the 5' and 3' ends of genes influence the location and kinetics of transcriptional initiation. The ultimate target of most epigenetic mechanisms may be the regulation of nucleosome occupancy, which in turn controls access to DNA at specific genomic locations.
Medical subject headings
- DNA
- Nucleosomes
- Transcription, Genetic