Connexin 43 signalling and cardioprotection.
review · Level V
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- Record sourced from PubMed, PMID 16387816.
- Also identified by PMC identifier 1861299.
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Abstract
Connexin (Cx) 43 is the predominant protein forming gap junctions and non-junctional hemichannels in ventricular myocardium. The Cx43 proteins are central to the cardioprotection afforded by ischaemic preconditioning (IP). The specific role of mitochondrial Cx43 in protection by IP is reviewed.
Medical subject headings
- Cell Communication
- Connexin 43
- Ischemic Preconditioning, Myocardial
- Mitochondria