Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 16401855.
- Also identified by PMC identifier 2752419.
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Abstract
The authors used voxel-based morphometry to compare the patterns of brain atrophy in two variants of pathologically confirmed frontotemporal lobar degeneration (FTLD): FTLD with motor neuron disease (FTLD-MND) and FTLD with ubiquitin-only-immunoreactive neuronal changes (FTLD-U). Patterns of atrophy were distinct and different from each other. A localized pattern of frontal lobe atrophy was found in FTLD-MND with a more widespread pattern of atrophy affecting the frontal and temporal lobes in FTLD-U.
Medical subject headings
- Atrophy
- Brain
- Dementia
- Motor Neuron Disease