A familial syndrome of unilateral polymicrogyria affecting the right hemisphere.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 16401865.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A number of familial syndromes of bilateral polymicrogyria (PMG) have been described, but reported unilateral PMG cases have generally been sporadic. The authors identified four families in which unilateral right-sided PMG on MRI was present in more than one individual, with pathologic confirmation in one. Core clinical features included contralateral hemiparesis, developmental delay, and focal seizures. The authors' findings suggest that unilateral PMG exists in a familial syndrome of probable germline genetic origin.
Medical subject headings
- Cerebral Cortex
- Functional Laterality
- Genetic Predisposition to Disease
- Nervous System Malformations