Plasma glutamine concentration: a guide in the management of urea cycle disorders.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 1640294.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Because increases in plasma glutamine concentrations are almost always associated with hyperammonemia in patients with urea cycle disorders, we determined the correlation between these two variables for 2 years in a child with ornithine transcarbamylase deficiency. A correlation coefficient of 0.77 (p less than 0.0001) was found. Hyperammonemia was rarely observed when plasma glutamine levels were near normal. These data suggest that one goal of therapy is the maintenance of plasma glutamine levels at or near normal values.
Medical subject headings
- Amino Acid Metabolism, Inborn Errors
- Ammonia
- Glutamine
- Ornithine Carbamoyltransferase Deficiency Disease