Mechanisms of increased acid secretion after eradication of Helicobacter pylori infection.
Level V
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- Record sourced from PubMed, PMID 16407378.
- Also identified by PMC identifier 1856493.
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Abstract
Eradication of Helicobacter pylori infection leads to recovery of gastric acid secretion in some individuals but the mechanism is not fully understood. In the short term, there is an impressive increase in expression of H+/K+-ATPase pumps without an increase in the number of parietal cells. Longer follow up studies are needed to see if the parietal cell mass eventually recovers.
Medical subject headings
- Gastric Acid
- Helicobacter Infections
- Helicobacter pylori