Homocysteine and risk in end-stage renal disease: a matter of context.

Zoccali, C; Mallamaci, F · Kidney Int · 2006

editorial · Level V

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Abstract

Like blood pressure and cholesterol, homocysteine shows a paradoxical inverse relationship with cardiovascular complications in end-stage renal disease (ESRD). A paper by Ducloux et al. in this issue adds perhaps decisive evidence on malnutrition-hypoalbuminemia as the main factor explaining the counterintuitive association between homocysteine and clinical outcome reported in previous studies.

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