Engineered membrane superchannel improves bioremediation potential of dioxin-degrading bacteria.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 16415854.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Sphingomonas sp. A1 possesses specialized membrane structures termed 'superchannels' that enable the direct incorporation of macromolecules into the cell. We have engineered two related sphingomonads, the dioxin-degrading S. wittichii RW1 and the polypropylene glycol-degrading S. subarctica IFO 16058(T), to incorporate this superchannel into their cell membranes. In both cases the bioremediation capability of the organisms was substantially increased pointing at the potential of this approach as a general strategy to improve bacterial degradation of hazardous compounds in the environment.
Medical subject headings
- Dioxins
- Genetic Enhancement
- Ion Channels
- Protein Engineering
- Sphingomonas