Sézary syndrome associated with granulomatous lesions during treatment with bexarotene.
case_report · Level V
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- Record sourced from PubMed, PMID 16433814.
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Abstract
Sézary syndrome (SS) is a leukaemic variant of cutaneous T-cell lymphoma (CTCL). We report a patient with SS who developed granulomatous lesions. These lesions broke out during treatment with bexarotene when the disease had appeared to stabilize. After a partial clinical remission the disease showed rapid progression and finally led to the patient's death. This contradicts the initial assessment, which considered the granulomatous inflammation as a good prognostic factor in CTCL.
Medical subject headings
- Antineoplastic Agents
- Drug Eruptions
- Granuloma
- Sezary Syndrome
- Tetrahydronaphthalenes