Factors influencing nerve regeneration in a trial of timcodar dimesylate.

Polydefkis, M; Sirdofsky, M; Hauer, P; Petty, B G; Murinson, B; McArthur, J C · Neurology · 2006

rct · Level II

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Abstract

The authors assessed the ability of the neurophilin compound, timcodar dimesylate, to accelerate the return of epidermal nerve fiber density (ENFD) after a standardized nerve injury in a randomized double blind, placebo controlled trial. While there was no difference in the regeneration rate between the treatment and placebo arms, the baseline ENFD (p = 0.006), height (p = 0.02), and race (p = 0.03) were associated with the regeneration rate.

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