Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot study.
prospective_cohort · Level II
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Abstract
The authors performed serial transcranial Doppler (TCD) and carbon dioxide reactivity (CO2R) testing in 20 aneurysmal subarachnoid hemorrhage patients to determine whether impaired cerebrovascular reactivity was associated with symptomatic vasospasm. Symptomatic vasospasm occurred in 9 of 14 patients with abnormal CO2R and in none of 6 patients with preserved reactivity (p = 0.011). Abnormal CO2R preceded the onset of vasospasm in 7 of 9 patients. Abnormal standard TCD testing was not associated with vasospasm.
Medical subject headings
- Carbon Dioxide
- Subarachnoid Hemorrhage
- Vasospasm, Intracranial