Linking chordate gene networks to cellular behavior in ascidians.

Davidson, Brad; Christiaen, Lionel · Cell · 2006

basic_science · Level V

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Abstract

Embryos of simple chordates called ascidians (sea squirts) have few cells, develop rapidly, and are transparent, enabling the in vivo fluorescent imaging of labeled cell lineages. Ascidians are also simple genetically, with limited redundancy and compact regulatory regions. This cellular and genetic simplicity is now being exploited to link comprehensive gene networks to the cellular events underlying morphogenesis.

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