T cells and T-cell receptors in acute renal failure.

Portilla, Didier; Okusa, Mark D · Kidney Int · 2006

editorial · Level V

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Abstract

T cells are activated by antigen-independent as well as antigen-dependent mechanisms during ischemia-reperfusion injury to the kidney. In the current issue, a study by Savransky et al. suggests that antigen-dependent activation of T-cell receptors further contributes to the pathogenesis of ischemia-reperfusion injury.

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