Evaluation of the effect of drugs on the cyst form of Toxoplasma gondii.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 1647421.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The cyst form of Toxoplasma gondii has been implicated as a cause of recrudescence of the latent infection in congenitally infected patients and in the immunocompromised host. A method was developed to evaluate the effect of drugs on the cyst form of the parasite and used to evaluate a variety of therapeutic agents. The most active compounds against the cyst form in vitro were arprinocid-N-oxide, azithromycin, and the hydroxynaphthoquinone 566C80.
Medical subject headings
- Anti-Infective Agents
- Toxoplasma