The human gene encoding phosphatidylinositol-3 kinase associated p85 alpha is at chromosome region 5q12-13.
basic_science · Level V
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Abstract
The human chromosomal location of the gene encoding the phosphatidylinositol-3 kinase associated protein, p85 alpha, has been determined by analysis of its segregation in rodent-human hybrids and by chromosome in situ hybridization using a complementary DNA clone, GRB-1. The gene for p85 alpha is at chromosome region 5q13, perhaps near the gene encoding another receptor associated signal transducing protein, the GTPase activating protein.
Medical subject headings
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- Genome, Human
- Phosphotransferases