Cancer risk assessment at the atomic level.
review · Level V
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- Record sourced from PubMed, PMID 16488985.
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Abstract
A flurry of articles on the structure of different domains of BRCA1 and BRCA2 have not only shed light on the biology of these proteins but have also raised hopes that these data could eventually be used to infer cancer association for a large number of inherited missense mutations whose effect on protein function is unclear.
Medical subject headings
- Mutation, Missense
- Neoplasms