Familial juvenile polyposis coli and colorectal cancer.
case_report · Level V
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- Record sourced from PubMed, PMID 1649688.
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Abstract
A 40-year-old mother and her 7-year-old son underwent colectomy for polyposis coli. Both colectomy specimens contained predominantly juvenile polyps. The mother's specimen also had numerous tubular adenomas and one 5-cm severely dysplastic villous adenoma without invasive carcinoma. Foci of adenomatous change in juvenile polyps were present in the son's specimen. The histologic features of both cases suggest a sequence of change from juvenile polyps to adenomatous polyps to cancer.
Medical subject headings
- Adenomatous Polyposis Coli
- Colorectal Neoplasms
- Precancerous Conditions