The rational design of an AIDS vaccine.

Douek, Daniel C; Kwong, Peter D; Nabel, Gary J · Cell · 2006

review · Level V

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Abstract

The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose significant challenges for vaccine development. AIDS vaccine design requires a scientifically driven, rational approach that encompasses the latest advances in viral molecular genetics, structural biology, and immunology.

Medical subject headings