Fatal varicella-zoster virus meningoradiculitis without skin involvement.

Dueland, A N; Devlin, M; Martin, J R; Mahalingam, R; Cohrs, R; Manz, H; Trombley, I; Gilden, D · Ann Neurol · 1991

case_report · Level V

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Abstract

A 77-year-old man with T-cell lymphoma developed an acute fatal meningoradiculitis of cranial nerve roots and cauda equina, pathologically and virologically confirmed to be caused by varicella-zoster virus. This is the first report of fatal varicella-zoster virus-induced neurological disease in the absence of skin lesions. Varicella-zoster virus should be included in the differential diagnosis of acute radiculoneuropathy in the immunocompromised patient, particularly because antiviral treatment for varicella-zoster virus exists.

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