Movin' on up: adipocytes become regulators of nutrient homeostasis.

Unger, Roger H; Elmquist, Joel K · Cell Metab · 2006

other · Level V

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Abstract

By locally infecting epididymal adipocytes of obese diabetic mice with the uncoupling protein-1 transgene, Yamada et al. (2006[this issue of Cell Metabolism]) unexpectedly induce leptin sensitivity with hypophagia and improvement in abnormal glucose and lipid abnormalities.

Medical subject headings