Expression of Toll-like receptors in the kidney: their potential role beyond infection.
editorial · Level V
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Abstract
Toll-like receptors (TLRs) recognize both exogenous microbial components and endogenous molecules to promote immune activation. Both immune and nonimmune renal cells express TLRs, which are involved in the pathogenesis of a number of kidney diseases, including pyelonephritis, Leptospira nephritis, immune-complex glomerulonephritis, ischemic/reperfusion injury, and rejection of kidney transplant.
Medical subject headings
- Kidney
- Toll-Like Receptors