Endocytosis conducts the cell signaling orchestra.

Polo, Simona; Di Fiore, Pier Paolo · Cell · 2006

review · Level V

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Abstract

Endocytosis is used by eukaryotic cells to regulate nutrient internalization, signal transduction, and the composition of the plasma membrane. However, a more complex picture is emerging, in which endocytic pathways integrate diverse signals, thereby contributing to a higher level of cellular and organismal organization. In this way, endocytosis and cell signaling are intertwined in many biological processes, such as cell motility and cell fate determination.

Medical subject headings