Hodgkin lymphoma, multiple myeloma, soft tissue sarcomas, insect repellents, and phenoxyherbicides.

Pahwa, Punam; McDuffie, Helen H; Dosman, James A; McLaughlin, John R; Spinelli, John J; Robson, Diane; Fincham, Shirley · J Occup Environ Med · 2006

case_control · Level III

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Abstract

The objective of this study was to determine if there is an additional risk of developing Hodgkin lymphoma, multiple myeloma, or soft tissue sarcoma as a consequence of exposure to a combination of phenoxyherbicides, rubber gloves, DEET (N, N-diethyl-m-toluamide), and sunlight compared with each of the individual chemicals. This was a population-based study of men with specific cancers and age, province-matched control subjects. No additional risk from these combinations of exposures of developing these three types of tumor was found in contrast to non-Hodgkin lymphoma. The mechanisms by which phenoxyherbicides contribute to the risk of multiple myeloma and non-Hodgkin lymphoma may be different.

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