Neuropsychological deficits in long-term frequent cannabis users.

Messinis, Lambros; Kyprianidou, Anthoula; Malefaki, Sonia; Papathanasopoulos, Panagiotis · Neurology · 2006

cross_sectional · Level IV

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Abstract

The authors examined neuropsychological functioning in 20 long-term (LT), 20 shorter term (ST) heavy frequent cannabis users, and 24 controls after abstinence for > or =24 hours prior to testing. LT users performed significantly worse on verbal memory and psychomotor speed. LT and ST users had a higher proportion of deficits on verbal fluency, verbal memory, attention, and psychomotor speed. Specific cognitive domains appear to deteriorate with increasing years of heavy frequent cannabis use.

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