Glycine prodrug facilitates memory retrieval in humans.

Schwartz, B L; Hashtroudi, S; Herting, R L; Handerson, H; Deutsch, S I · Neurology · 1991

rct · Level II

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Abstract

Modulation of glycine concentrations in the brain influences learning and memory functions in experimental animals. We administered milacemide, a glycine prodrug, or placebo to young and older healthy adults, who performed a word-retrieval task. Milacemide administration increased the number of words retrieved and decreased the latency with which these words were retrieved for both young and older adults.

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