Long-term follow-up of patients with thalamic deep brain stimulation for epilepsy.

Andrade, D M; Zumsteg, D; Hamani, C; Hodaie, M; Sarkissian, S; Lozano, A M; Wennberg, R A · Neurology · 2006

case_series · Level IV

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Abstract

The authors describe long-term follow-up (mean, 5 years) in patients with anterior (AN) (n = 6) or centromedian (n = 2) thalamic deep brain stimulation (DBS) for epilepsy. Five patients (all AN) had > or = 50% seizure reduction, although benefit was delayed in two until years 5 to 6, after changes in antiepileptic drugs. DBS electrode implantation in AN patients was followed by seizure reduction 1 to 3 months before active stimulation, raising the possibility of a beneficial microthalamotomy effect.

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