Induction of withdrawal-like symptoms in a small randomized, controlled trial of opioid blockade in frequent tanners.

Kaur, Mandeep; Liguori, Anthony; Lang, Wei; Rapp, Stephen R; Fleischer, Alan B; Feldman, Steven R · J Am Acad Dermatol · 2006

rct · Level II

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Abstract

Frequent tanning has reinforcing properties. We tested whether opioid antagonism blocks potential reinforcing effect of indoor tanning in 8 frequent tanners and 8 infrequent tanner control subjects. Opioid blockade reduced ultraviolet preference in frequent tanners. Four of 8 frequent tanners, but no infrequent tanners, exhibited withdrawal-like symptoms with naltrexone administration. A limitation of this study is its small size.

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