Useful plants of dermatology. VIII. The false hellebore (Veratrum californicum).

McFerren, Marcus A · J Am Acad Dermatol · 2006

Level V

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Abstract

Plants have and continue to provide medicine with an abundance of pharmacologically interesting and useful chemicals. In recent years, cyclopamine, a steroidal alkaloid isolated from Veratrum californicum, has been instrumental in dissecting the sonic hedgehog pathway. This brief report outlines cyclopamine's discovery with discussion of its potential application to clinical dermatology.

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