LRP6 holds the key to the entry of anthrax toxin.
editorial · Level V
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Abstract
In this issue of Cell, it is demonstrated that the low-density lipoprotein receptor-related protein 6 (LRP6) promotes endocytosis of the anthrax toxin into cells. LRP6 acts as a coreceptor with either TEM8 or CMG2, the two previously identified receptors for anthrax toxin.
Medical subject headings
- Antigens, Bacterial
- Bacterial Toxins
- Receptors, LDL