Structural complexity in ubiquitin recognition.
review · Level V
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- Record sourced from PubMed, PMID 16564007.
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Abstract
Ubiquitinated proteins are sorted into distinct pathways via association with several classes of ubiquitin binding domain-containing proteins. A virtual explosion in the field of ubiquitin binding proteins has revealed several new classes and interactions with distinct surfaces on ubiquitin, providing a clearer understanding of how sorting of ubiquitinated proteins is achieved.
Medical subject headings
- Guanine Nucleotide Exchange Factors
- Signal Transduction
- Ubiquitin