Indicted: worms caught using steroids.
review · Level V
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Abstract
Three recent papers provide new insights into endocrinology in the worm Caenorhabditis elegans. These studies identify natural steroid ligands for the DAF-12 nuclear receptor, define a new enzyme in the hormone biosynthetic pathway, and clarify the role of endocrine signaling in adult longevity.
Medical subject headings
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cytochrome P-450 Enzyme System
- Receptors, Cytoplasmic and Nuclear
- Receptors, Steroid
- Signal Transduction
- Steroids