Orbital cellulitis in a patient receiving infliximab for Ankylosing spondylitis.
case_report · Level V
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- Record sourced from PubMed, PMID 16564827.
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Abstract
To describe a case of orbital cellulitis arising in a patient treated with an anti-TNFalpha agent. Single interventional case report. A 42-year-old man developed severe unilateral orbital cellulitis while receiving infliximab (Remicade, Centocor) treatment for Ankylosing spondylitis (AS) as part of the open-label phase of a trial conducted at our tertiary referral center. Cultures grew Staphylococcus aureus. Infliximab treatment was stopped and the patient made a full recovery after receiving appropriate antibiotic therapy. Infliximab therapy was resumed after three weeks. Clinical vigilance is warranted when treating patients with anti-TNFalpha agents as these are associated with a diverse and growing number of ophthalmic complications. Resolved infection does not preclude the use of such agents.
Medical subject headings
- Antibodies, Monoclonal
- Cellulitis
- Eye Infections, Bacterial
- Orbital Diseases
- Spondylitis, Ankylosing
- Staphylococcal Infections