MyoD1 protein expression in alveolar soft part sarcoma as confirmatory evidence of its skeletal muscle nature.
case_report · Level V
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Abstract
A typical case of alveolar soft part sarcoma was found to express in a strong and widespread fashion the marker MyoD1 protein. This nuclear phosphoprotein is the product of a regulatory gene that controls the commitment of a cell to myogenic lineage; it therefore provides strong and perhaps definitive evidence in support of the skeletal muscle nature of this enigmatic neoplasm.
Medical subject headings
- Muscle Proteins
- Muscles
- Sarcoma
- Soft Tissue Neoplasms