Macrolide prescriptions and erythromycin resistance of Streptococcus pyogenes.
cross_sectional · Level IV
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Abstract
This study shows a significant association between the number of macrolide prescriptions reimbursed by the Italian National Health Service and resistance of Streptococcus pyogenes to erythromycin in children from a region in northern Italy with high prevalence of erythromycin resistance. Recent prescription of a macrolide (especially azithromycin) is a predictor of erythromycin resistance, as well as a possible risk factor for resistance at a community level.
Medical subject headings
- Drug Resistance, Bacterial
- Erythromycin
- Macrolides
- Streptococcal Infections
- Streptococcus pyogenes