Clinical implications of basic neuroscience research. I: Protein kinases, ionic channels, and genes.
review · Level V
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Abstract
Clinical implications of three areas of basic neuroscience research are described in this review paper. These areas include: (1) the discovery of protein kinase C and its implications for diabetic neuropathy, (2) analysis of single ionic channels and the basis of Lambert-Eaton myasthenic syndrome and cystic fibrosis, and (3) the cloning of genes for Duchenne muscular dystrophy and cystic fibrosis and new approaches to the treatment of these diseases.
Medical subject headings
- Cystic Fibrosis
- Diabetic Neuropathies
- Lambert-Eaton Myasthenic Syndrome
- Protein Kinases