Structure of simian virus 40 at 3.8-A resolution.
basic_science · Level V
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- Record sourced from PubMed, PMID 1659663.
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Abstract
The crystallographically determined structure of simian virus 40 shows that the 72 pentamers of viral protein VP1, which form the outer shell, have identical conformations except for the C-terminal arms of their subunits. Five arms emerge from each pentamer and insert into neighbouring pentamers. This tying together of standard building blocks allows for the required variability in packing geometry without sacrificing specificity.
Medical subject headings
- Capsid
- Capsid Proteins
- Simian virus 40