ACE inhibition and glomerular repair: restructuring or regeneration?
editorial · Level V
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Abstract
In this issue of Kidney International, Andrea Remuzzi et al. convincingly demonstrate glomerular repair in spontaneous renal disease by ACE inhibition. These findings provoke questions about how ACE inhibition (or AT1R blockade) can on the one hand actually repair some diseased kidneys while on the other interfering with normal renal development or the recovery of other diseased kidneys.
Medical subject headings
- Angiotensin-Converting Enzyme Inhibitors
- Glomerulosclerosis, Focal Segmental
- Kidney Glomerulus