Hibernation proteins: preparing for life in the freezer.

Hastings, Michael H; Ebling, Francis J P · Cell · 2006

review · Level V

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Abstract

Hibernation is an extreme response to a seasonal environment, yet we know almost nothing about how it is timed or how vital cellular functions are sustained in the face of plummeting body temperature. In this issue of Cell, kondo et al. (2006) identify a liver-derived protein complex as an essential coordinator of this adaptation to the depredations of winter.

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