Building bridges to the cortex.
review · Level V
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- Record sourced from PubMed, PMID 16615886.
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Abstract
Innervation of the neocortex by the thalamus is dependent on the precise coordination of spatial and temporal guidance cues. In this issue of Cell, work by López-Bendito et al.(2006) reveals that tangentially migrating cells within the ventral telencephalon are essential for axonal navigation between the thalamus and the neocortex, a process apparently mediated by Neuregulin-1/ErbB4 short- and long-range signaling.
Medical subject headings
- Axons
- Cell Movement
- Cerebral Cortex
- Neuregulin-1
- Thalamus