When a motor goes bad: a kinesin regulates neuronal survival.
editorial · Level V
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Abstract
In this issue of Cell, Midorikawa et al. (2006) demonstrate that the kinesin superfamily member KIF4, a microtubule-based molecular motor, regulates the survival of electrically active neurons in the developing brain by modulating the function of poly(ADP-ribose) polymerase-1 in an unexpected way.
Medical subject headings
- Cell Survival
- Kinesins
- Nerve Tissue Proteins
- Neurons