Mycophenolate mofetil in dermatomyositis: is it safe?

Rowin, J; Amato, A A; Deisher, N; Cursio, J; Meriggioli, M N · Neurology · 2006

case_series · Level IV

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Abstract

The authors report 10 patients with idiopathic dermatomyositis treated with mycophenolate mofetil in combination with corticosteroids. Successful steroid taper without disease relapse was achieved in six patients; however, in three patients, treatment was associated with opportunistic infections, leading to death in one patient. The disproportionately high rate of opportunistic infections in this group is considered.

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